PhD & MS programs > Medical Biophysics: Biomolecular Imaging > Ph.D. Minor in Biomolecular Imaging > Introduction to Biomolecular Imaging
Introduction to Biomolecular Imaging, F592
Course Description
The IUPUI campus has strengths in a wide variety of imaging sciences, and this course is dedicated to introducing these key concepts and capabilities to graduate students. The goal of the course is to introduce key concepts that carry through all imaging modalities, and provide examples of how these concepts of modern imaging apply in the real world at the level of cellular and molecular imaging. The course will include a survey of the principles and application of modern imaging methods. The course will be team taught by a group of faculty from diverse departments within the IUPUI campus. Tom Hurley is the course director
Prerequisites
Undergraduate level calculus, physics, organic and inorganic chemistry or permission of the instructor. Designed as a fall course for first year graduate students.
Course Instructors
| Instructor | Department |
|---|---|
| Berbari | Engineering |
| Dunn | Nephrology |
| Fang | Computer & Information Science |
| Gattone | Anatomy & Cell Biology |
| Hurley | Biochemistry & Molecular Biology |
| Naumann | Chemistry |
| Pavalko | Physiology |
| Tuceryan | Computer & Information Science |
| Yokota | Biomedical Engineering and Anatomy & Cell Biology |
Required and Recommended Texts
No textbook will be required for this course.
Evaluation and Grading
Two week-long take-home exams will be given. Final exam is non-cumulative. Grades weighted by number of lectures covered in each exam. Final grading will be on an A,B,C scale.
Syllabus
| Lecture | Topics | |
|---|---|---|
| Introduction: Imaging biological processes | ||
| Why imaging? | ||
| Every atom as a potential reporter | ||
| Signal generation and detection | ||
| Light: sources and interactions | ||
| Light detection: devices and limits | ||
| Molecular forces | ||
| Example of molecular forces: Cell Adhesion | ||
| Molecular force detection | ||
| Review session & hand out mid-term exam | ||
| Mid-Term Take Home Exam | ||
| Magnetism | ||
| X-Ray | ||
| Electrons: | ||
| Building an image | ||
| Introduction: from zero to 4 dimensions | ||
| Digital Signal Processing | ||
| Generating Images | ||
| Two & three dimensional digital image analysis | ||
| Computational basis for visualization | ||
| Protein Crystal Structure | ||
| Computational basis for quantification | ||
| Image deconvolution: | ||
| Data management | ||
| Review session and hand out final | ||
| Final Take Home Exam | ||
